Set Aside Your Proud Certainty Good advice for everyone. In his preamble to “The Theory of Relativity,” Einstein implored his reader to, “set aside your proud certainty” because he was about to present something quite revolutionary, iconoclastic, and, as he discovered for many years after publication, challenging to be broadly…

Artificial Intelligence, Biotechnology, and New Drug Discovery Text to breakthrough. Artificial intelligence models, such as Open AI’s DALL-E2 program, are trained to generate pictures from almost any text request. …

Nicholas Mitsakos Volatile stock and bond markets are not going away anytime soon, and investment strategies focused on discipline, market-tested algorithms, and the patience to withstand near-term turbulence will continue to deliver better results. As US stocks have dropped about 25% and US long-term treasuries dropped nearly 30%, specific strategies…

The most ambitious ideas are yet to be discovered. Most current innovations have yet to reach their potential, and new innovations are essential to address the most critical issues we confront, whether that is climate change, food scarcity, water shortages, or more effective distribution of innovation itself. Artificial Intelligence Advanced…

Since Finance is one of the areas of our investment focus, and it is going through significant turmoil because of FTX and related bankruptcies, I wanted to comment on this situation. This is still a sideshow compared to the significant opportunities created by the global disruption of finance. Specifically, I…

A New Vision for Artificial Intelligence Artificial intelligence has received a lot of attention and hype for what it can do, but perhaps more attention is given to the fear of what it could do. There is a different way to think about artificial intelligence and its relevance as a…

Nicholas Mitsakos The Next 10 Years Turbulent times are here to stay. Intense and more frequent volatility will define the next decade. Carnage The onslaught of market-making bad news seems almost a daily event. …

What’s Next? Predictions usually end up being nonsense. We simply draw a trajectory from what we know today. But innovation is a discontinuity. Things are unpredictable because innovation does not come from consensus thinking. It comes from small groups and individuals with a spark of entrepreneurship, intelligence, and vision. One…

Anything to Anyone Anytime A monster is on the loose. The Internet, an extraordinary new platform for communication and business, became accessible to anyone. Companies like Netscape, eBay, Amazon, and Yahoo paved the way so that by 2000 the future was in the Internet’s vast expanse. During this boom, fortunes…